Invention Grant
US07935833B2 Compound containing carboxylate ester and N2S2 ligand bi-functional groups and manufacturing method thereof 有权
含羧酸酯和N2S2配位体双官能团的化合物及其制备方法

Compound containing carboxylate ester and N2S2 ligand bi-functional groups and manufacturing method thereof
Abstract:
A compound containing carboxylate ester and N2S2 ligand bi-functional groups and a manufacturing method thereof are disclosed. The S in the N2S2 ligand of the compound containing carboxylate ester and N2S2 ligand bi-functional groups includes a protective group so as to avoid to be oxidized and easy storage. In a complex reaction, the protective group is automatically released As to the active carboxylate ester, it is for reacting with compounds having amino groups such as amines, amino acids, peptides, or protein etc while the N2S2 ligand is for bonding with technetium or rhenium so as to form neutral complex. The compound containing carboxylate ester and N2S2 ligand bi-functional groups is applied to radiopharmaceuticals such as contrast agents for tissues and target agents.
Information query
Patent Agency Ranking
0/0