A method and a device for reconfiguration in a wireless system utilizing flexible layer one (FLO). In proposed solution one TFC (Transport Format Combination) is selected and reserved (504) exclusively for signalling use. The TFC may contain only one active transport channel and always utilize the same CRC and transport block size in order to unambiguously define the proper settings for signalling. Considering uplink transmission in a wireless system and special case of TFCI (Transport Format Combination Identifier) size change due to the TFCS (Transport Format Combination Set) reconfiguration that also generates a need to switch to a new dedicated basic physical subchannel (DBPSCH); whenever the network notices that the mobile station does not switch to the new DBPSCH (518), it concludes that the TFCS reconfiguration message sent was lost and stays with the existing configuration (520). Otherwise the new configuration is taken into use (514).