A method of efficient library characterization of a circuit of a logic gate having a plurality of transistors and a plurality of nodes defining interconnection points in the circuit is disclosed. The method includes determining a plurality of vectors for a plurality of arcs. Each of the plurality of vectors represents possible data bits to inputs and nodes of the logic gate. The method selects a plurality of substantially distinct vectors from the plurality of vectors for each of the plurality of arcs, and performs circuit pruning for each of the plurality of substantially distinct vectors, taking each one substantially distinct vector at a time. The circuit pruning includes identifying an active circuit for each vector. The active circuit is identified by determining which circuit features are activated when applying a particular one of the substantially distinct vectors. Then, the circuit simulations limited to a plurality of transistors in the active circuit are performed. The circuit pruning and circuit simulations are repeated for remaining ones of the plurality of substantially distinct vectors. The results of the circuit simulations are then stored on a non-volatile compute readable media, for each active circuit corresponding to each of the plurality of substantially distinct vectors.