A high-definition multimedia interface (HDMI) receiver recovers high speed encoded data which are transmitted differentially over data channels of a lossy cable, along with a clock. Inter symbol interference, high-frequency loss, skew between the clock and data channels, and differential skew within a differential signal are compensated by analog circuits which are automatically tuned for best performance by observing the quality of the recovered analog signal. Oversampling is used to provide a 24-bit digital representation of the analog signal for determining the quality of the signal. A corresponding method of deskewing a differential signal and a system and circuit therefor are also provided.