Invention Grant
- Patent Title: Dissolution testing with in-situ gravimetric volume measurement
- Patent Title (中): 用原位重量体积测量进行溶出度测试
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Application No.: US12262033Application Date: 2008-10-30
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Publication No.: US07938032B2Publication Date: 2011-05-10
- Inventor: C. J. Anthony Fernando
- Applicant: C. J. Anthony Fernando
- Applicant Address: US CA Santa Clara
- Assignee: Agilent Technologies, Inc.
- Current Assignee: Agilent Technologies, Inc.
- Current Assignee Address: US CA Santa Clara
- Main IPC: G01N13/00
- IPC: G01N13/00 ; G01N33/15

Abstract:
A dissolution test apparatus includes a vessel support member, weight sensors, a movable component, a media transport cannula, a pump, and an electronic controller. The vessel support member receives vessels. A weight sensor is located at each vessel site. Each weight sensor contacts a vessel and transmits a measurement signal indicative of the weight of the vessel and any contents therein. The movable component moves the media transport cannula toward a vessel site. The pump establishes media flow between the media transport cannula and the selected vessel. The controller communicates with the weight sensors and may also communicate with the pump. Based on the measurement signals received from the weight sensors, the electronic controller may calculate the volume of media in a given vessel. The electronic controller may also control media flows to or from the vessels by transmitting control signals to the pump assembly.
Public/Granted literature
- US20100107752A1 DISSOLUTION TESTING WITH IN-SITU GRAVIMETRIC VOLUME MEASUREMENT Public/Granted day:2010-05-06
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