Invention Grant
US07939068B2 Antagonizing signal transduction in dorsal root ganglion cells in a subject with IL-31 antagonists
有权
IL-31拮抗剂受试者背根神经节细胞的拮抗信号转导
- Patent Title: Antagonizing signal transduction in dorsal root ganglion cells in a subject with IL-31 antagonists
- Patent Title (中): IL-31拮抗剂受试者背根神经节细胞的拮抗信号转导
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Application No.: US12395095Application Date: 2009-02-27
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Publication No.: US07939068B2Publication Date: 2011-05-10
- Inventor: Yue Yao , Janine Bilsborough
- Applicant: Yue Yao , Janine Bilsborough
- Applicant Address: US WA Seattle
- Assignee: ZymoGenetics, Inc.
- Current Assignee: ZymoGenetics, Inc.
- Current Assignee Address: US WA Seattle
- Agent Robyn Adams
- Main IPC: A61K39/395
- IPC: A61K39/395 ; A61K38/00 ; C07K16/28 ; C07K14/435 ; C07K14/00
Abstract:
Use of antagonists to IL-31 are used to treat inflammation and pain by inhibiting, preventing, reducing, minimizing, limiting or minimizing stimulation in neuronal tissues. Such antagonists include antibodies and fragments, derivative, or variants thereof. Symptoms such as pain, tingle, sensitization, tickle associated with neuropathies are ameliorated.
Public/Granted literature
- US20100221244A1 ANTAGONIZING SIGNAL TRANSDUCTION IN DORSAL ROOT GANGLION CELLS IN A SUBJECT WITH IL-31 ANTAGONISTS Public/Granted day:2010-09-02
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