Invention Grant
US07939077B2 Humanized antibody against fibroblast growth factor-8 and antibody fragment thereof
失效
针对成纤维细胞生长因子-8的人源化抗体及其抗体片段
- Patent Title: Humanized antibody against fibroblast growth factor-8 and antibody fragment thereof
- Patent Title (中): 针对成纤维细胞生长因子-8的人源化抗体及其抗体片段
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Application No.: US10482105Application Date: 2002-06-28
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Publication No.: US07939077B2Publication Date: 2011-05-10
- Inventor: Kenya Shitara , Kazuyasu Nakamura , Maiko Hirota , Naoki Shimada
- Applicant: Kenya Shitara , Kazuyasu Nakamura , Maiko Hirota , Naoki Shimada
- Applicant Address: JP Tokyo
- Assignee: Kyowa Hakko Kirin Co., Ltd.
- Current Assignee: Kyowa Hakko Kirin Co., Ltd.
- Current Assignee Address: JP Tokyo
- Agency: Nixon & Vanderhye, P.C.
- Priority: JPP.2001-196176 20010628
- International Application: PCT/JP02/06591 WO 20020628
- International Announcement: WO03/002608 WO 20030109
- Main IPC: A61K39/395
- IPC: A61K39/395 ; C07H21/04 ; C07K16/22 ; C12N5/10 ; C12N15/13 ; C12N15/63 ; C12P21/08
Abstract:
The present invention relates to an antibody against FGF-8, particularly a humanized antibody against FGF-8 and the antibody fragment thereof, a DNA sequence encoding the above antibody or the antibody fragment, a vector comprising the DNA sequence and a host cell transformed by the vector, a production process of the above antibody or the antibody fragment using the host cell, and a therapeutic agent and a diagnostic agent for cancer using the antibody or the antibody fragment.
Public/Granted literature
- US20040253234A1 Humanized antibody against fibroblast growth factor-8 and antibody fragment thereof Public/Granted day:2004-12-16
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