Invention Grant
- Patent Title: Expression profile algorithm and test for cancer prognosis
- Patent Title (中): 表达谱算法和癌症预后检测
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Application No.: US12406831Application Date: 2009-03-18
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Publication No.: US07939261B2Publication Date: 2011-05-10
- Inventor: Joffre B. Baker , John L. Bryant , Soonmyung Paik , Steven Shak
- Applicant: Joffre B. Baker , John L. Bryant , Soonmyung Paik , Steven Shak
- Applicant Address: US CA Redwood City US PA Pittsburgh
- Assignee: Genomic Health, Inc.,NSABP Foundation, Inc.
- Current Assignee: Genomic Health, Inc.,NSABP Foundation, Inc.
- Current Assignee Address: US CA Redwood City US PA Pittsburgh
- Agency: Bozicevic, Field and Francis LLP
- Agent Paula A. Borden
- Main IPC: C12Q1/68
- IPC: C12Q1/68 ; G06F19/00

Abstract:
The present invention provides a noninvasive, quantitative test for prognosis determination in cancer patients. The test relies on measurements of the tumor levels of certain messenger RNAs (mRNAs). These mRNA levels are inserted into a polynomial formula (algorithm) that yields a numerical recurrence score, which indicates recurrence risk.
Public/Granted literature
- US20090280490A1 Expression Profile Algorithm and Test for Cancer Prognosis Public/Granted day:2009-11-12
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