Invention Grant
- Patent Title: Compositions and methods for treating and diagnosing cancer
- Patent Title (中): 用于治疗和诊断癌症的组合物和方法
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Application No.: US12512655Application Date: 2009-07-30
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Publication No.: US07939263B2Publication Date: 2011-05-10
- Inventor: Michael F. Clarke , Xinhao Wang , John A. Lewicki , Austin L. Gurney
- Applicant: Michael F. Clarke , Xinhao Wang , John A. Lewicki , Austin L. Gurney
- Applicant Address: US MI Ann Arbor US CA Mountain View
- Assignee: The Regents of the University of Michigan,OncoMed Pharmaceuticals, Inc.
- Current Assignee: The Regents of the University of Michigan,OncoMed Pharmaceuticals, Inc.
- Current Assignee Address: US MI Ann Arbor US CA Mountain View
- Agency: Casimir Jones, S.C.
- Main IPC: C12Q1/68
- IPC: C12Q1/68
Abstract:
The present invention relates to compositions and methods for treating, characterizing, and diagnosing cancer. In particular, the present invention provides gene expression profiles and signatures associated with solid tumor stem cells, as well as novel stem cell cancer markers useful for the diagnosis, characterization, prognosis and treatment of solid tumor stem cells. More particularly, the present invention identifies two profiles of cancer stem cells useful for the diagnosis, characterization, and treatment of cancer and cancer metastases. The invention also provides a variety of reagents such as stem cell gene signatures for use in the diagnosis and management of cancer.
Public/Granted literature
- US20100093556A1 COMPOSITIONS AND METHODS FOR TREATING AND DIAGNOSING CANCER Public/Granted day:2010-04-15
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