Invention Grant
- Patent Title: Method for differentiating between factor XIII deficiency states and fibrinogen deficiency states by means of thrombelastographic techniques
- Patent Title (中): 通过血栓形成技术区分因子XIII缺陷状态和纤维蛋白原缺乏状态的方法
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Application No.: US11883916Application Date: 2006-02-06
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Publication No.: US07939288B2Publication Date: 2011-05-10
- Inventor: Erhardt Wrabetz , Hubert Metzner , Wolfgang Korte
- Applicant: Erhardt Wrabetz , Hubert Metzner , Wolfgang Korte
- Applicant Address: DE Marburg
- Assignee: CSL Behring GmbH
- Current Assignee: CSL Behring GmbH
- Current Assignee Address: DE Marburg
- Agency: Finnegan, Henderson, Farabow, Garrett & Dunner, L.L.P.
- Priority: DE102005005824 20050208
- International Application: PCT/EP2006/001015 WO 20060206
- International Announcement: WO2006/084648 WO 20060817
- Main IPC: C12Q1/56
- IPC: C12Q1/56

Abstract:
The invention relates to a method for determining a factor XIII deficiency, a method for determining a fibrinogen deficiency, and a method for differentiating between a factor XIII deficiency and a fibrinogen deficiency by means of thrombelastographic techniques. On the basis of the evaluation of the thrombelastographic parameters, a rapid and a selective substitution of factor XIII and/or of fibrinogen in deficiency states is possible.
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