Invention Grant
- Patent Title: Fluorescent probe
- Patent Title (中): 荧光探针
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Application No.: US12911348Application Date: 2010-10-25
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Publication No.: US07939330B2Publication Date: 2011-05-10
- Inventor: Tetsuo Nagano , Eita Sasaki , Hirotatsu Kojima , Tomoya Hirano , Kazuya Kikuchi
- Applicant: Tetsuo Nagano , Eita Sasaki , Hirotatsu Kojima , Tomoya Hirano , Kazuya Kikuchi
- Applicant Address: JP Tokyo
- Assignee: Tetsuo Nagano
- Current Assignee: Tetsuo Nagano
- Current Assignee Address: JP Tokyo
- Agency: Greenblum & Bernstein, P.L.C.
- Priority: JP2004-045643 20040223
- Main IPC: G01N21/78
- IPC: G01N21/78 ; G01N31/00 ; G01N31/22 ; C07D209/08 ; C07D249/18

Abstract:
A fluorescent probe which specifically and efficiently traps nitrogen monoxide, zinc ion etc. to emit fluorescence is provided.A compound represented by the following general formula (I): [wherein R1 and R2 represent hydrogen atom, or a group represented by the following formula (A): (wherein X1 to X4 represent hydrogen atom, an alkyl group, or a protective group for amino group, and m and n represent 0 or 1); R3 and R4 represent hydrogen atom, a C1-6 alkyl group, or a C1-6 alkoxy group; R5 to R12 represent hydrogen atom, sulfo group, phospho group, a halogen atom, or a C1-6 alkyl group; R13 and R14 represent a C1-18 alkyl group; Z1 represents oxygen atom, sulfur atom, or —N(R15)— (wherein R15 represents hydrogen atom, or a C1-6 alkyl group); Y1 and Y2 represent —C(═O)—, —C(═S)—, or —C(R16)(R17) (wherein R16 and R17 represent a C1-6 alkyl group); and M− represents a counter ion in a number required for neutralizing the charge].
Public/Granted literature
- US20110038803A1 FLUORESCENT PROBE Public/Granted day:2011-02-17
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