Invention Grant
US07939535B2 Benzo[D]isoxazol-3-yl-piperazin derivatives useful as modulators of dopamine D3 receptors
失效
苯并[D]异恶唑-3-基 - 哌嗪衍生物,可用作多巴胺D3受体的调节剂
- Patent Title: Benzo[D]isoxazol-3-yl-piperazin derivatives useful as modulators of dopamine D3 receptors
- Patent Title (中): 苯并[D]异恶唑-3-基 - 哌嗪衍生物,可用作多巴胺D3受体的调节剂
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Application No.: US12560471Application Date: 2009-09-16
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Publication No.: US07939535B2Publication Date: 2011-05-10
- Inventor: Luca Gobbi , Georg Jaeschke , Rosa Maria Rodriguez Sarmiento , Lucinda Steward
- Applicant: Luca Gobbi , Georg Jaeschke , Rosa Maria Rodriguez Sarmiento , Lucinda Steward
- Applicant Address: US NJ Nutley
- Assignee: Hoffman-La Roche Inc.
- Current Assignee: Hoffman-La Roche Inc.
- Current Assignee Address: US NJ Nutley
- Agent George W. Johnston; Patricia S. Rocha-Tramaloni; Kimberly J. Prior
- Priority: EP08164903 20080923
- Main IPC: A61K31/497
- IPC: A61K31/497 ; C07D419/04
![Benzo[D]isoxazol-3-yl-piperazin derivatives useful as modulators of dopamine D3 receptors](/abs-image/US/2011/05/10/US07939535B2/abs.jpg.150x150.jpg)
Abstract:
The present invention provides compounds of the general formula (I), having affinity and selectivity for the dopamine D3 receptors, their manufacture, pharmaceutical compositions containing them and their use for the therapeutic and/or prophylactic treatment of cognitive disorders.
Public/Granted literature
- US20100075985A1 BENZO[D]ISOXAZOL-3-YL-PIPERAZIN DERIVATIVES USEFUL AS MODULATORS OF DOPAMINE D3 RECEPTORS Public/Granted day:2010-03-25
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