Invention Grant
- Patent Title: Controlled-release composition for topical application and a method of delivering an active agent to a substrate
- Patent Title (中): 用于局部施用的控释组合物和将活性剂递送至底物的方法
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Application No.: US10576991Application Date: 2004-10-27
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Publication No.: US07939570B2Publication Date: 2011-05-10
- Inventor: Victor A. Raul , Xavier Jean-Paul Thomas , Anne K. Shim , Gerald K. Schalau, II , Janelle L. Cabala
- Applicant: Victor A. Raul , Xavier Jean-Paul Thomas , Anne K. Shim , Gerald K. Schalau, II , Janelle L. Cabala
- Applicant Address: US MI Midland
- Assignee: Dow Corning Corporation
- Current Assignee: Dow Corning Corporation
- Current Assignee Address: US MI Midland
- Agency: Dinsmore & Shohl LLP
- International Application: PCT/US2004/035619 WO 20041027
- International Announcement: WO2005/044232 WO 20050519
- Main IPC: A01N25/00
- IPC: A01N25/00 ; A61K47/00 ; A61Q5/12
Abstract:
A controlled-release composition for topical application to a substrate includes an oil-in-water emulsion and an active agent incorporated into the oil-in-water emulsion. The oil-in-water emulsion is substantially free of lipophilic solvent and is formed by mechanical inversion of a water-in-oil emulsion. The water-in-oil emulsion includes a silicone component, a surfactant, and water. A method of delivering the active agent to the substrate provides the oil-in-water emulsion and incorporates the active agent into the oil-in-water emulsion for delivery of the active agent to the substrate upon application of the oil-in-water emulsion to the substrate.
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