Invention Grant
US07941212B2 Method of delivering a drug using a medical device with a coating comprising a self-assembled molecular structure
有权
使用具有包含自组装分子结构的涂层的医疗装置递送药物的方法
- Patent Title: Method of delivering a drug using a medical device with a coating comprising a self-assembled molecular structure
- Patent Title (中): 使用具有包含自组装分子结构的涂层的医疗装置递送药物的方法
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Application No.: US12043891Application Date: 2008-03-06
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Publication No.: US07941212B2Publication Date: 2011-05-10
- Inventor: Connie S. Kwok , Charles D. Claude
- Applicant: Connie S. Kwok , Charles D. Claude
- Applicant Address: US CA Santa Clara
- Assignee: Advanced Cardiovascular Systems, Inc.
- Current Assignee: Advanced Cardiovascular Systems, Inc.
- Current Assignee Address: US CA Santa Clara
- Agency: Squire, Sanders & Dempsey (US) LLP
- Main IPC: A61N1/30
- IPC: A61N1/30
Abstract:
A method for local delivery of a drug is provided. The method comprises the acts of (a) implanting a medical device carrying a drug-containing coating in a patient for the sustained local delivery of the drug, wherein at least a portion of the coating is transformed from crystalline structure to amorphous structure; and (b) applying an electric current for an interval of time to the device for increasing the rate of release of the drug, wherein the coating is further transformed from crystalline structure to amorphous structure; and (c) terminating the current after an interval of time, wherein at least a portion of the amorphous structure in the coating is at least partially restored to crystalline structure.
Public/Granted literature
- US20080154232A1 COATINGS COMPRISING SELF-ASSEMBLED MOLECULAR STRUCTURES AND A METHOD OF DELIVERING A DRUG USING THE SAME Public/Granted day:2008-06-26
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