Invention Grant
- Patent Title: Fluorescent substrates for neurotransmitter transporters
- Patent Title (中): 荧光底物用于神经递质转运蛋白
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Application No.: US11832905Application Date: 2007-08-02
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Publication No.: US07947255B2Publication Date: 2011-05-24
- Inventor: Randy D. Blakely , John N. Mason , Ian D. Tomlinson , Sandra J. Rosenthal
- Applicant: Randy D. Blakely , John N. Mason , Ian D. Tomlinson , Sandra J. Rosenthal
- Applicant Address: US TN Nashville
- Assignee: Vanderbilt University
- Current Assignee: Vanderbilt University
- Current Assignee Address: US TN Nashville
- Agency: Fulbright & Jaworski
- Main IPC: A61K49/00
- IPC: A61K49/00 ; G01N33/52
Abstract:
The invention is based on the finding that IDT307 and analogs thereof are fluorescent substrates transported by several neurotransmitter transporters. Provided are methods for the analysis of neurotransmitter transport and binding using IDT307 and its analogs. The invention also provides rapid methods for screening for modulators of neurotransmitter transport.
Public/Granted literature
- US20080108102A1 FLUORESCENT SUBSTRATES FOR NEUROTRANSMITTER TRANSPORTERS Public/Granted day:2008-05-08
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