Invention Grant
- Patent Title: Compositions and methods of tolerizing a primate to an antigen
- Patent Title (中): 将灵长类动物耐受抗原的组合物和方法
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Application No.: US11486293Application Date: 2006-07-13
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Publication No.: US07947272B2Publication Date: 2011-05-24
- Inventor: Mark Frewin , Herman Waldmann , Scott Gorman , Geoff Hale , Patricia Rao , Tadeusz Kornaga , Douglas Ringler , Stephen Cobbold , Dawn Winsor-Hines
- Applicant: Mark Frewin , Herman Waldmann , Scott Gorman , Geoff Hale , Patricia Rao , Tadeusz Kornaga , Douglas Ringler , Stephen Cobbold , Dawn Winsor-Hines
- Applicant Address: US MA Cambridge GB Oxford GB Cambridge
- Assignee: Tolerx, Inc.,Isis Innovation, Ltd.,Cambridge University Technical Services, Ltd.
- Current Assignee: Tolerx, Inc.,Isis Innovation, Ltd.,Cambridge University Technical Services, Ltd.
- Current Assignee Address: US MA Cambridge GB Oxford GB Cambridge
- Agent Elliot M. Olstein; Raymond J. Lillie
- Main IPC: A61K39/395
- IPC: A61K39/395
Abstract:
Inducing tolerance in a primate by use of a compound, or a combination of at least two compounds, that has certain characteristics when tested in vitro. The compound, alone or in combination, is preferably TRX1 antibody and the compound or combination is preferably used in accordance with a specified dosing regimen.
Public/Granted literature
- US20080160016A1 Compositions and methods of tolerizing a primate to an antigen Public/Granted day:2008-07-03
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