Invention Grant
- Patent Title: Aqueous pharmaceutical formulation
- Patent Title (中): 水性药物制剂
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Application No.: US12099284Application Date: 2008-04-08
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Publication No.: US07947293B2Publication Date: 2011-05-24
- Inventor: Dieter Gillessen , Juergen Jaeger
- Applicant: Dieter Gillessen , Juergen Jaeger
- Applicant Address: CH Reinach
- Assignee: Arpida AG
- Current Assignee: Arpida AG
- Current Assignee Address: CH Reinach
- Agency: Dickstein Shapiro LLP
- Main IPC: A61K9/00
- IPC: A61K9/00 ; A01N43/54 ; C07D405/06

Abstract:
The invention concerns a stable aqueous pharmaceutical composition comprising 5-[(2RS)-2-cyclopropyl-7,8-dimethoxy-2H-1-benzopyran-5-ylmethyl]-pyrimidine-2,4-diamine in form of the water soluble methanesulfonic acid salt, a physiological sodium chloride solution, ethanol and Povidone 12 PF, the liquid having a pH of over and above 4.8, but not higher than 5.2, and wherein the oxygen amount is controlled to be 0.8 ppm or less; which can be sterilized by filtration and/or by heated treatment, stored for longer time periods and which can be use for bolus injection or diluted for i.v. infusion.
Public/Granted literature
- US20090253722A1 AQUEOUS PHARMACEUTICAL FORMULATION Public/Granted day:2009-10-08
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