Invention Grant
- Patent Title: Methods of diagnosing pre-eclampsia or eclampsia
- Patent Title (中): 诊断先兆子痫或子痫的方法
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Application No.: US12221623Application Date: 2008-08-04
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Publication No.: US07947449B2Publication Date: 2011-05-24
- Inventor: S. Ananth Karumanchi , Sharon Maynard , Vikas P. Sukhatme
- Applicant: S. Ananth Karumanchi , Sharon Maynard , Vikas P. Sukhatme
- Applicant Address: US MA Boston
- Assignee: Beth Israel Deaconess Medical Center
- Current Assignee: Beth Israel Deaconess Medical Center
- Current Assignee Address: US MA Boston
- Agency: Clark & Elbing LLP
- Agent Kristina Bieker-Brady; Kimya F. Harris
- Main IPC: C12Q1/68
- IPC: C12Q1/68 ; G01N33/53 ; G01N33/542
Abstract:
Disclosed herein are methods for diagnosing pre-eclampsia and eclampsia. Also disclosed herein are methods for treating pre-eclampsia and eclampsia using compounds that increase VEGF or PlGF levels or compounds that decrease sFlt-1 levels. Compounds that inhibit the binding of VEGF or PlGF to sFlt1- are also disclosed herein for the treatment of pre-eclampsia or eclampsia.
Public/Granted literature
- US20090004669A1 Methods of diagnosing pre-eclampsia or eclampsia Public/Granted day:2009-01-01
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