Invention Grant
- Patent Title: Variant activin receptor polypeptides
- Patent Title (中): 变异激活素受体多肽
-
Application No.: US12074877Application Date: 2008-03-05
-
Publication No.: US07947646B2Publication Date: 2011-05-24
- Inventor: Jeonghoon Sun , Lei-Ting Tony Tam , Hui-Quan Han , Keith Soo-Nyung Kwak , Xiaolan Zhou
- Applicant: Jeonghoon Sun , Lei-Ting Tony Tam , Hui-Quan Han , Keith Soo-Nyung Kwak , Xiaolan Zhou
- Applicant Address: US CA Thousand Oaks
- Assignee: Amgen Inc.
- Current Assignee: Amgen Inc.
- Current Assignee Address: US CA Thousand Oaks
- Agent Lawrence B. Bugaisky
- Main IPC: A61K38/00
- IPC: A61K38/00
Abstract:
The present invention provides variant activin IIB soluble receptor polypeptides and proteins capable of binding and inhibiting the activities of activin A, myostatin, or GDF-11. The present invention also provides polynucleotides, vectors and host cells capable of producing the variant polypeptides and proteins. Compositions and methods for treating muscle-wasting and other diseases and disorders are also provided.
Public/Granted literature
- US20090227497A1 Variant activin receptor polypeptides and uses thereof Public/Granted day:2009-09-10
Information query
IPC分类:
