Invention Grant
- Patent Title: iRNA agents targeting VEGF
- Patent Title (中): 靶向VEGF的iRNA试剂
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Application No.: US11078073Application Date: 2005-03-11
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Publication No.: US07947659B2Publication Date: 2011-05-24
- Inventor: Antonin de Fougerolles , Maria Frank-Kamenetsky , Muthiah Manoharan , Kallanthottathil G. Rajeev , Philipp Hadwiger
- Applicant: Antonin de Fougerolles , Maria Frank-Kamenetsky , Muthiah Manoharan , Kallanthottathil G. Rajeev , Philipp Hadwiger
- Applicant Address: US MA Cambridge
- Assignee: Alnylam Pharmaceuticals, Inc.
- Current Assignee: Alnylam Pharmaceuticals, Inc.
- Current Assignee Address: US MA Cambridge
- Agency: Fenwick & West LLP
- Main IPC: A61K31/70
- IPC: A61K31/70 ; C07H21/04
Abstract:
The features of the present invention relate to compounds, compositions and methods useful for modulating the expression of vascular endothelial growth factor (VEGF), such as by the mechanism of RNA interference (RNAi). The compounds and compositions include iRNA agents that can be unmodified or chemically-modified.
Public/Granted literature
- US20060094032A1 iRNA agents targeting VEGF Public/Granted day:2006-05-04
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