Invention Grant
- Patent Title: Heterocyclic benzodiazepine CGRP receptor antagonists
- Patent Title (中): 杂环苯并二氮杂CGRP受体拮抗剂
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Application No.: US11988986Application Date: 2006-07-25
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Publication No.: US07947678B2Publication Date: 2011-05-24
- Inventor: Theresa M. Williams
- Applicant: Theresa M. Williams
- Applicant Address: US NJ Rahway
- Assignee: Merck Sharp & Dohme Corp.
- Current Assignee: Merck Sharp & Dohme Corp.
- Current Assignee Address: US NJ Rahway
- Agent Gerald M. Devlin; Raynard Yuro
- International Application: PCT/US2006/028835 WO 20060725
- International Announcement: WO2007/016087 WO 20070208
- Main IPC: A61P25/00
- IPC: A61P25/00 ; A61K31/55 ; C07D243/10 ; C07D487/12
Abstract:
Compounds of formula I: (where variables R2, R7, D, W, X, Y and Z are as described herein) which are antagonists of CGRP receptors and which are useful in the treatment or prevention of diseases in which the CGRP is involved, such as migraine. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which CGRP is involved.
Public/Granted literature
- US20090105228A1 Heterocyclic benzodiazepine cgrp receptor antagonists Public/Granted day:2009-04-23
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