Invention Grant
US07947694B2 Substituted pyrazolo[3,4-D]pyrimidines as cell cycle kinase inhibitors
有权
取代的吡唑并[3,4-D]嘧啶作为细胞周期激酶抑制剂
- Patent Title: Substituted pyrazolo[3,4-D]pyrimidines as cell cycle kinase inhibitors
- Patent Title (中): 取代的吡唑并[3,4-D]嘧啶作为细胞周期激酶抑制剂
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Application No.: US11813654Application Date: 2006-01-09
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Publication No.: US07947694B2Publication Date: 2011-05-24
- Inventor: Eddy Jean Edgard Freyne , Jean Fernand Armand Lacrampe , Timothy Pietro Suren Perera , Peter Ten Holte , Yannick Aimé Eddy Ligny , Delphine Yvonne Raymonde Lardeau , Tom Lavrijssen
- Applicant: Eddy Jean Edgard Freyne , Jean Fernand Armand Lacrampe , Timothy Pietro Suren Perera , Peter Ten Holte , Yannick Aimé Eddy Ligny , Delphine Yvonne Raymonde Lardeau , Tom Lavrijssen
- Applicant Address: BE
- Assignee: Janssen Pharmaceutica NV
- Current Assignee: Janssen Pharmaceutica NV
- Current Assignee Address: BE
- Priority: EP05100215 20050114
- International Application: PCT/EP2006/050096 WO 20060109
- International Announcement: WO2006/074984 WO 20060720
- Main IPC: C07D487/04
- IPC: C07D487/04 ; A61K31/519 ; A61P35/00
![Substituted pyrazolo[3,4-D]pyrimidines as cell cycle kinase inhibitors](/abs-image/US/2011/05/24/US07947694B2/abs.jpg.150x150.jpg)
Abstract:
This invention comprises the novel compounds of formula (I) wherein R1, R2, R3, R4, R5, R6, X1 and X2 have defined meanings, having cell cycle kinase inhibiting enzymatic activity, their preparation, compositions containing them and their use as a medicine.
Public/Granted literature
- US20080039477A1 Pyrazolopyrimidines as Cell Cycle Kinase Inhibitors Public/Granted day:2008-02-14
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