Invention Grant
US07947696B2 2-amino-4-phenylquinazoline derivatives and the use thereof as HSP90 modulators
失效
2-氨基-4-苯基喹唑啉衍生物及其作为HSP90调节剂的用途
- Patent Title: 2-amino-4-phenylquinazoline derivatives and the use thereof as HSP90 modulators
- Patent Title (中): 2-氨基-4-苯基喹唑啉衍生物及其作为HSP90调节剂的用途
-
Application No.: US11914604Application Date: 2006-04-24
-
Publication No.: US07947696B2Publication Date: 2011-05-24
- Inventor: Hans-Michael Eggenweiler , Michael Wolf , Hans-Peter Buchstaller
- Applicant: Hans-Michael Eggenweiler , Michael Wolf , Hans-Peter Buchstaller
- Applicant Address: DE Darmstadt
- Assignee: Merck Patent GmbH
- Current Assignee: Merck Patent GmbH
- Current Assignee Address: DE Darmstadt
- Agency: Millen, White, Zelano & Branigan, P.C.
- Priority: DE102005022977 20050519
- International Application: PCT/EP2006/003734 WO 20060424
- International Announcement: WO2006/122631 WO 20061123
- Main IPC: A61K31/517
- IPC: A61K31/517
Abstract:
Novel phenylquinazoline derivatives of the formula (I), in which R1, R2, R3, R4 and R5 have the meanings indicated in Claim 1, are HSP90 inhibitors and can be used for the preparation of a medicament for the treatment of diseases in which the inhibition, regulation and/or modulation of HSP90 plays a role.
Public/Granted literature
- US20080214586A1 2-Amino-4-Phenylquinazoline Derivatives and the Use Thereof as Hsp90 Modulators Public/Granted day:2008-09-04
Information query
IPC分类:
