Invention Grant
- Patent Title: Toxin detection method
- Patent Title (中): 毒素检测方法
-
Application No.: US12306863Application Date: 2007-07-03
-
Publication No.: US07947808B2Publication Date: 2011-05-24
- Inventor: Kanenari Ohishi , Tadashi Baba , Keiichi Hiramatsu , Yasuo Nakatomi
- Applicant: Kanenari Ohishi , Tadashi Baba , Keiichi Hiramatsu , Yasuo Nakatomi
- Applicant Address: JP Tokyo
- Assignee: Juntendo University School of Medicine
- Current Assignee: Juntendo University School of Medicine
- Current Assignee Address: JP Tokyo
- Agency: Foley & Lardner LLP
- Agent Stephen A. Bent
- Priority: JP2006-183535 20060703
- International Application: PCT/JP2007/063278 WO 20070703
- International Announcement: WO2008/004536 WO 20080110
- Main IPC: C07K16/00
- IPC: C07K16/00 ; C12P21/08
Abstract:
According to the present invention, an antibody against a Panton-Valentine leukocidin toxin contained in Staphylococcus aureus, a method and a kit for detecting the toxin with the use of the antibody, and a pharmaceutical composition containing an antibody against a Panton-Valentine leukocidin toxin for treating PVL infection caused by Staphylococcus aureus containing PVL are provided. Also, an antibody which is capable of binding to Panton-Valentine leukocidin F and has no cross-reactivity to LukD and/or HlgB and an antibody which is capable of binding to Panton-Valentine leukocidin S and has no cross-reactivity to at least one of LukE, HlgC, and HlgA are provided.
Public/Granted literature
- US20100092487A1 TOXIC DETECTION METHOD Public/Granted day:2010-04-15
Information query
