Invention Grant
- Patent Title: Antibodies that bind specifically to human RON protein
- Patent Title (中): 与人RON蛋白特异性结合的抗体
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Application No.: US12313589Application Date: 2008-11-21
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Publication No.: US07947811B2Publication Date: 2011-05-24
- Inventor: Daniel Pereira , Jennifer O'Toole
- Applicant: Daniel Pereira , Jennifer O'Toole
- Applicant Address: US NY New York
- Assignee: ImClone LLC
- Current Assignee: ImClone LLC
- Current Assignee Address: US NY New York
- Agent Nicole S. Woods
- Main IPC: C07K16/28
- IPC: C07K16/28 ; C07K16/00 ; A61K39/395
Abstract:
The invention provides antibodies or fragments thereof, including human antibodies, specific for Macrophage-Stimulating Protein Receptor (MSP-R or RON), which inhibit RON activation. Also provided are methods to inhibit RON, particularly the use of RON antibodies to treat diseases such as cancer.
Public/Granted literature
- US20090136510A1 Inhibition of macrophage-stimulating protein receptor (RON) and methods of treatment thereof Public/Granted day:2009-05-28
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