Invention Grant
- Patent Title: Polyelectrolyte precipitation and purification of proteins
- Patent Title (中): 聚电解质沉淀和纯化蛋白质
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Application No.: US11972010Application Date: 2008-01-10
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Publication No.: US07947813B2Publication Date: 2011-05-24
- Inventor: Robert L. Fahrner , Jayme Franklin , Paul McDonald , Thanmaya Peram , Vikram Sisodiya , Corazon Victa
- Applicant: Robert L. Fahrner , Jayme Franklin , Paul McDonald , Thanmaya Peram , Vikram Sisodiya , Corazon Victa
- Applicant Address: US CA South San Francisco
- Assignee: Genentech, Inc.
- Current Assignee: Genentech, Inc.
- Current Assignee Address: US CA South San Francisco
- Agency: Genentech, Inc.
- Agent Alex Andrus
- Main IPC: C07K1/22
- IPC: C07K1/22 ; C07K1/32
Abstract:
Methods are presented for isolating and purifying proteins by adding a polyelectrolyte to a cell culture fluid, such as a harvested cell culture fluid, and precipitating a protein-polyelectrolyte complex or a complex of impurities and the polyelectrolyte.
Public/Granted literature
- US20080193981A1 POLYELECTROLYTE PRECIPITATION AND PURIFICATION OF PROTEINS Public/Granted day:2008-08-14
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