Invention Grant
US07947830B2 Substituted propenyl piperazine derivatives as novel inhibitors of histone deacetylase
有权
取代的丙烯基哌嗪衍生物作为组蛋白脱乙酰酶的新型抑制剂
- Patent Title: Substituted propenyl piperazine derivatives as novel inhibitors of histone deacetylase
- Patent Title (中): 取代的丙烯基哌嗪衍生物作为组蛋白脱乙酰酶的新型抑制剂
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Application No.: US11626215Application Date: 2007-01-23
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Publication No.: US07947830B2Publication Date: 2011-05-24
- Inventor: Sven Franciscus Anna Van Brandt , Kristof Van Emelen , Patrick René Angibaud , Laurence Françoise Bernadette Marconnet-Decrane , Janine Arts
- Applicant: Sven Franciscus Anna Van Brandt , Kristof Van Emelen , Patrick René Angibaud , Laurence Françoise Bernadette Marconnet-Decrane , Janine Arts
- Applicant Address: BE Beerse
- Assignee: Janssen Pharmaceutica N.V.
- Current Assignee: Janssen Pharmaceutica N.V.
- Current Assignee Address: BE Beerse
- Agency: Patton Boggs LLP
- Priority: EP04077171 20040728
- Main IPC: C07D417/00
- IPC: C07D417/00 ; C07D413/00 ; C07D403/00
Abstract:
This invention comprises the novel compounds of formula (I) wherein R1, R2, R3, R4 and X have defined meanings, having histone deacetylase inhibiting enzymatic activity; their preparation, compositions containing them and their use as a medicine.
Public/Granted literature
- US20070135424A1 SUBSTITUTED PROPENYL PIPERAZINE DERIVATIVES AS NOVEL INHIBITORS OF HISTONE DEACETYLASE Public/Granted day:2007-06-14
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