The present invention relates to systems and methods for the optimized selection and delivery of one or more advertisements from among one or more advertising campaigns. The method of the present invention comprises generating one or more media plans identifying execution parameters for the optimized selection and delivery of one or more advertisements. One or more advertisements organized according to one or more advertisement campaigns are retrieved. Additionally, advertiser specified constraint and target values associated with the one or more advertisements are retrieved. A forecast for the performance of the one or more advertisements is generated. A media plan is generated for the one or more advertisements according to the constraint and target values, as well as the forecast data. The one or more advertisements are distributed according to the execution parameters identified by the media plan.