Invention Grant
- Patent Title: Inhibitors of p38
- Patent Title (中): p38的抑制剂
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Application No.: US12062495Application Date: 2008-04-03
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Publication No.: US07951809B2Publication Date: 2011-05-31
- Inventor: Guy W. Bemis , Francesco G. Salituro , John P. Duffy , John E. Cochran , Edmund M. Harrington , Mark A. Murcko , Keith P. Wilson , Michael Su , Vincent P. Galullo
- Applicant: Guy W. Bemis , Francesco G. Salituro , John P. Duffy , John E. Cochran , Edmund M. Harrington , Mark A. Murcko , Keith P. Wilson , Michael Su , Vincent P. Galullo
- Applicant Address: US MA Cambridge
- Assignee: Vertex Pharmaceuticals Incorporated
- Current Assignee: Vertex Pharmaceuticals Incorporated
- Current Assignee Address: US MA Cambridge
- Agency: Virtual Law Partners LLP
- Agent David A. Roise
- Main IPC: C07D239/70
- IPC: C07D239/70 ; A61K31/519
Abstract:
The present invention relates to inhibitors of p38, a mammalian protein kinase involved cell proliferation, cell death and response to extracellular stimuli. The invention also relates to methods for producing these inhibitors. The invention also provides pharmaceutical compositions comprising the inhibitors of the invention and methods of utilizing those compositions in the treatment and prevention of various disorders.
Public/Granted literature
- US20090203702A1 INHIBITORS OF p38 Public/Granted day:2009-08-13
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