Invention Grant
US07956056B2 Certain 1H-imidazo[4,5-B]pyrazin-2(3H)-ones and 1H-imidazo[4,5-B]pyrazin-2-ols, compositions thereof, and methods for their use
有权
某些1H-咪唑并[4,5-B]吡嗪-2(3H) - 酮和1H-咪唑并[4,5-B]吡嗪-2-醇及其使用方法
- Patent Title: Certain 1H-imidazo[4,5-B]pyrazin-2(3H)-ones and 1H-imidazo[4,5-B]pyrazin-2-ols, compositions thereof, and methods for their use
- Patent Title (中): 某些1H-咪唑并[4,5-B]吡嗪-2(3H) - 酮和1H-咪唑并[4,5-B]吡嗪-2-醇及其使用方法
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Application No.: US12573730Application Date: 2009-10-05
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Publication No.: US07956056B2Publication Date: 2011-06-07
- Inventor: Alex Muci , Jeffrey T. Finer , Pu-Ping Lu , Alan James Russell , Bradley P. Morgan , David J. Morgans, Jr.
- Applicant: Alex Muci , Jeffrey T. Finer , Pu-Ping Lu , Alan James Russell , Bradley P. Morgan , David J. Morgans, Jr.
- Applicant Address: US CA South San Francisco
- Assignee: Cytokinetics, Inc.
- Current Assignee: Cytokinetics, Inc.
- Current Assignee Address: US CA South San Francisco
- Agency: Foley & Lardner LLP
- Main IPC: A61K31/495
- IPC: A61K31/495
![Certain 1H-imidazo[4,5-B]pyrazin-2(3H)-ones and 1H-imidazo[4,5-B]pyrazin-2-ols, compositions thereof, and methods for their use](/abs-image/US/2011/06/07/US07956056B2/abs.jpg.150x150.jpg)
Abstract:
Provided is at least one chemical entity chosen from compounds of Formula I and Formula II: and pharmaceutically acceptable salts thereof, compositions thereof, and methods for their use in modulating one or more of skeletal myosin, skeletal actin, skeletal tropomyosin, skeletal troponin C, skeletal troponin I, skeletal troponin T, skeletal muscle, and skeletal sarcomere.
Public/Granted literature
- US20100093741A1 CERTAIN CHEMICAL ENTITIES, COMPOSITIONS AND METHODS Public/Granted day:2010-04-15
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