Invention Grant
US07956064B2 Fused tricyclic compounds as serine-threonine protein kinase and PARP modulators
有权
融合的三环化合物作为丝氨酸 - 苏氨酸蛋白激酶和PARP调节剂
- Patent Title: Fused tricyclic compounds as serine-threonine protein kinase and PARP modulators
- Patent Title (中): 融合的三环化合物作为丝氨酸 - 苏氨酸蛋白激酶和PARP调节剂
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Application No.: US11849230Application Date: 2007-08-31
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Publication No.: US07956064B2Publication Date: 2011-06-07
- Inventor: Peter C. Chua , Jeffrey P. Whitten
- Applicant: Peter C. Chua , Jeffrey P. Whitten
- Applicant Address: US CA San Diego
- Assignee: Cylene Pharmaceuticals, Inc.
- Current Assignee: Cylene Pharmaceuticals, Inc.
- Current Assignee Address: US CA San Diego
- Agency: Cooley LLP
- Main IPC: A61K31/44
- IPC: A61K31/44 ; C07D471/12
Abstract:
The invention relates in part to fused tricyclic compounds having certain biological activities that include, but are not limited to, inhibiting cell proliferation, modulating protein kinase activity and modulating polymerase activity. The fused tricyclic compounds of the invention can modulate casein kinase (CK) activity and/or poly(ADP-ribose)polymerase (PARP) activity. The invention also relates in part to methods for using such fused tricyclic compounds.
Public/Granted literature
- US20090264423A2 SERINE-THREONINE PROTEIN KINASE AND PARP MODULATORS Public/Granted day:2009-10-22
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