Invention Grant
US07956077B2 2-{-3,′2-(phenyl)-oxazol-4-ylmethoxyl-cyclohexyl methoxy}-propionic acid derivatives used as peroxisome proliferator-activated receptor (PPAR) ligands for the treatment of hyperlipidemia and diabetes
有权
用作治疗高脂血症和糖尿病的过氧化物酶体增殖物激活受体（PPAR）配体的2 - { - 3，“2-（苯基） - 恶唑-4-基甲氧基] - 环己基甲氧基} - 丙酸衍生物
- Patent Title: 2-{-3,′2-(phenyl)-oxazol-4-ylmethoxyl-cyclohexyl methoxy}-propionic acid derivatives used as peroxisome proliferator-activated receptor (PPAR) ligands for the treatment of hyperlipidemia and diabetes
- Patent Title (中): 用作治疗高脂血症和糖尿病的过氧化物酶体增殖物激活受体（PPAR）配体的2 - { - 3，“2-（苯基） - 恶唑-4-基甲氧基] - 环己基甲氧基} - 丙酸衍生物
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Application No.: US11671673Application Date: 2007-02-06
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Publication No.: US07956077B2Publication Date: 2011-06-07
- Inventor: Heiner Glombik , Christian Stapper , Eugen Falk , Stefanie Keil , Hans-Ludwig Schaefer , Wolfgang Wendler , Stephanie Knieps
- Applicant: Heiner Glombik , Christian Stapper , Eugen Falk , Stefanie Keil , Hans-Ludwig Schaefer , Wolfgang Wendler , Stephanie Knieps
- Applicant Address: DE Frankfurt Am Main
- Assignee: Sanofi-Aventis Deutschland GmbH
- Current Assignee: Sanofi-Aventis Deutschland GmbH
- Current Assignee Address: DE Frankfurt Am Main
- Agency: Scully, Scott, Murphy & Presser, P.C.
- Priority: DE102004039532 20040814
- Main IPC: A01N43/76
- IPC: A01N43/76 ; C07D263/34
Abstract:
The present invention comprises compounds and compositions for the treatment of metabolic disorders and more particularly, those insulin-related metabolic disorders of the blood such as hyperlipidemia, diabetes, insulin-resistence and the like comprising acetic acid derivatives with cyclohexylmethoxy substituents and their salts. Known as peroxisome proliferator-activated receptors (PPAR) agonists/antagonists, the invention relates to compounds of formula I wherein the various substituent R-groups are more specifically defined herein.
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