Invention Grant
US07956189B2 Maleate, tosylate, fumarate and oxalate salts of 5-(1-(S)-amino-2-hydroxyethyl)-N-[(2,4-difluorophenyl)-methy]-2-[8-methoxy-2-(triflouromethy)-5-quinoline]-4-oxazolecarboxamide and preparation process therefore
失效
5-（1-（S） - 氨基-2-羟乙基）-N - [（2,4-二氟苯基） - 甲基] -2- [8-甲氧基-2-（三氟甲基）三氟甲磺酸盐，马来酸盐，甲苯磺酸盐，富马酸盐和草酸盐 ）-5-喹啉] -4-氧杂二甲酰胺及其制备方法
![Maleate, tosylate, fumarate and oxalate salts of 5-(1-(S)-amino-2-hydroxyethyl)-N-[(2,4-difluorophenyl)-methy]-2-[8-methoxy-2-(triflouromethy)-5-quinoline]-4-oxazolecarboxamide and preparation process therefore](/docs/US/2011-06-07/US07956189B2/abs.jpg.600x600.jpg)
- Patent Title: Maleate, tosylate, fumarate and oxalate salts of 5-(1-(S)-amino-2-hydroxyethyl)-N-[(2,4-difluorophenyl)-methy]-2-[8-methoxy-2-(triflouromethy)-5-quinoline]-4-oxazolecarboxamide and preparation process therefore
- Patent Title (中): 5-（1-（S） - 氨基-2-羟乙基）-N - [（2,4-二氟苯基） - 甲基] -2- [8-甲氧基-2-（三氟甲基）三氟甲磺酸盐，马来酸盐，甲苯磺酸盐，富马酸盐和草酸盐 ）-5-喹啉] -4-氧杂二甲酰胺及其制备方法
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Application No.: US11891351Application Date: 2007-08-10
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Publication No.: US07956189B2Publication Date: 2011-06-07
- Inventor: Xiaoming Chen , Xiao Chen , Jianguo Yin , Xiaoyong Fu , David J. Blythin , Rongze Kuang , Ho-Jane Shue , Scott Trzaska , Chee-Wah Tang , Vincenzo Liotta , Zaher Shabani
- Applicant: Xiaoming Chen , Xiao Chen , Jianguo Yin , Xiaoyong Fu , David J. Blythin , Rongze Kuang , Ho-Jane Shue , Scott Trzaska , Chee-Wah Tang , Vincenzo Liotta , Zaher Shabani
- Applicant Address: US NJ Kenilworth
- Assignee: Schering Corporation
- Current Assignee: Schering Corporation
- Current Assignee Address: US NJ Kenilworth
- Agent Patricia A. Shatynski; Valerie J. Camara
- Main IPC: C07D215/38
- IPC: C07D215/38
![Maleate, tosylate, fumarate and oxalate salts of 5-(1-(S)-amino-2-hydroxyethyl)-N-[(2,4-difluorophenyl)-methy]-2-[8-methoxy-2-(triflouromethy)-5-quinoline]-4-oxazolecarboxamide and preparation process therefore](/abs-image/US/2011/06/07/US07956189B2/abs.jpg.150x150.jpg)
Abstract:
Disclosed are maleate, tosylate, fumarate, and oxalate salts of the compound 5-(1(S)-Amino-2-Hydroxyethyl)-N-[(2,4-Difluorophenyl)-Methyl]-2-[8-Methoxy-2-(Trifluoromethyl)-5-Quinoline]-4-Oxazolecarboxamide, represented by Formula I, and methods of preparing the same.
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