An automotive drive system for a high voltage electric motor comprises a microcontroller and ECU powered by a low voltage (12 volt) bus net which controls the drives of a high voltage inverter powered by a 100 volt or higher source, which, in turn, drives the motor. To provide good electrical insulation between the low voltage and high voltage systems, the low voltage control signals are produced by a low voltage signal transmitter chip which has a small integral antenna which wirelessly communicates with the antenna of a high voltage driver IC which drives the power devices of the high voltage inverter. The two IC chips are separated by a suitable isolation distance and may be bare chips, individually packaged chips or co-packed chips. Plural control IC chips and driver IC chips can communicate with one another for adverse control functions, including “smart” functions.