The method obtains an interference detection result by detecting sampled digital signals in real time in a transform domain, then maps the interference detection result into an interference suppression pulse function on the basis of a unit noise pulse function, and carries out interference suppression filtering in the transform domain according to the interference suppression pulse function. The present invention is capable of detecting narrowband interference such as monotone, frequency modulation, and phase modulation interferences in a receive channel adaptively in real-time, and suppressing the interference adaptively according to the quantity, energy and bandwidth of the interference, so as to reduce the influence of the interference. Therefore, the present invention may enhance robustness of the communication system against interference. Moreover, the present invention does not need multiple notch devices, costs low and may be implemented simply and reliably.