Invention Grant
US07959925B2 Trimeric OX40-immunoglobulin fusion protein and methods of use
有权
三聚OX40-免疫球蛋白融合蛋白及其使用方法
- Patent Title: Trimeric OX40-immunoglobulin fusion protein and methods of use
- Patent Title (中): 三聚OX40-免疫球蛋白融合蛋白及其使用方法
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Application No.: US12618678Application Date: 2009-11-13
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Publication No.: US07959925B2Publication Date: 2011-06-14
- Inventor: Andrew D. Weinberg , Nicholas P. Morris , Carmen Romerdaue
- Applicant: Andrew D. Weinberg , Nicholas P. Morris , Carmen Romerdaue
- Applicant Address: US WA Seattle
- Assignee: Providence Health System
- Current Assignee: Providence Health System
- Current Assignee Address: US WA Seattle
- Agency: Klarquist Sparkman, LLP
- Main IPC: A61K39/00
- IPC: A61K39/00 ; A61K39/385 ; C12P21/08 ; C07K16/00 ; C07H21/04
Abstract:
Compositions including a trimeric OX-40 fusion protein are disclosed. Also disclosed are methods for enhancing the immune response of a mammal to an antigen by engaging the OX-40 receptor on the surface of T-cells involving administering to the mammal a composition comprising a trimeric OX-40 fusion protein and a pharmaceutically acceptable carrier.
Public/Granted literature
- US20100136032A1 TRIMERIC OX40-IMMUNOGLOBULIN FUSION PROTEIN AND METHODS OF USE Public/Granted day:2010-06-03
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