Invention Grant
- Patent Title: Method for rapid generation of mature dendritic cells
- Patent Title (中): 快速生成成熟树突细胞的方法
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Application No.: US12058213Application Date: 2008-03-28
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Publication No.: US07959934B2Publication Date: 2011-06-14
- Inventor: Dennis M. Klinman , Mayda Gursel , Daniela Verthelyi
- Applicant: Dennis M. Klinman , Mayda Gursel , Daniela Verthelyi
- Applicant Address: US MD Rockville
- Assignee: The United States of America as represented by the Secretary of the Department of Health and Human Services
- Current Assignee: The United States of America as represented by the Secretary of the Department of Health and Human Services
- Current Assignee Address: US MD Rockville
- Agency: Klarquist Sparkman, LLP
- Main IPC: A61K45/00
- IPC: A61K45/00 ; A61K39/00
Abstract:
Novel methods of rapidly generating dendrtic cells are disclosed herein. The methods include contacting a dendritic cell precursor with a D ODN to generate a mature dendritic cell. In one specific, non-limiting example, the method includes contacting the dendritic cell precursor or the mature dendritic cell with an antigen. The methods are of use both in vitro and in vivo.
Public/Granted literature
- US20080241176A1 METHOD FOR RAPID GENERATION OF MATURE DENDRITIC CELLS Public/Granted day:2008-10-02
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