Invention Grant
- Patent Title: Gene signature of early hypoxia to predict patient survival
- Patent Title (中): 早期缺氧的基因特征预测患者生存
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Application No.: US12113373Application Date: 2008-05-01
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Publication No.: US07960114B2Publication Date: 2011-06-14
- Inventor: Renaud G. Seigneuric , Maud H. W. Starmans , Glenn Fung , Balaji Krishnapuram , Dimitry S. A. Nuyten , Arie van Erk , Michael Gaston Magagnin , Kasper M. Rouschop , Sriram Krishnan , R. Bharat Rao , Christoffel Theodorus Anthonius Evelo , Adrian Campbell Begg , Bradly G. Wouters , Philippe Lambin
- Applicant: Renaud G. Seigneuric , Maud H. W. Starmans , Glenn Fung , Balaji Krishnapuram , Dimitry S. A. Nuyten , Arie van Erk , Michael Gaston Magagnin , Kasper M. Rouschop , Sriram Krishnan , R. Bharat Rao , Christoffel Theodorus Anthonius Evelo , Adrian Campbell Begg , Bradly G. Wouters , Philippe Lambin
- Applicant Address: US PA Malvern
- Assignee: Siemens Medical Solutions USA, Inc.
- Current Assignee: Siemens Medical Solutions USA, Inc.
- Current Assignee Address: US PA Malvern
- Agent Joshua B. Ryan
- Main IPC: C12Q1/68
- IPC: C12Q1/68

Abstract:
The present invention provides methods and compositions for predicting patient responses to cancer treatment using hypoxia gene signatures. These methods can comprise measuring in a biological sample from a patient the levels of gene expression of a group of the genes designated herein. The present invention also provides for microarrays that can detect expression from a group of genes.
Public/Granted literature
- US20090130096A1 Gene Signature of Early Hypoxia to Predict Patient Survival Public/Granted day:2009-05-21
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