Invention Grant
- Patent Title: Antisense modulation of stearoyl-CoA desaturase expression
- Patent Title (中): 硬脂酰-CoA去饱和酶表达的反义调制
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Application No.: US11613144Application Date: 2006-12-19
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Publication No.: US07960358B2Publication Date: 2011-06-14
- Inventor: Sanjay Bhanot , Kenneth W. Dobie , John G. Geisler , Mark J. Graham
- Applicant: Sanjay Bhanot , Kenneth W. Dobie , John G. Geisler , Mark J. Graham
- Applicant Address: US CA Carlsbad
- Assignee: Isis Pharmaceuticals, Inc.
- Current Assignee: Isis Pharmaceuticals, Inc.
- Current Assignee Address: US CA Carlsbad
- Agency: Jones Day
- Main IPC: A61K31/70
- IPC: A61K31/70 ; C07H21/04
Abstract:
Antisense compounds, compositions and methods are provided for modulating the expression of stearoyl-CoA desaturase. The compositions comprise antisense compounds, particularly antisense oligonucleotides, targeted to nucleic acids encoding stearoyl-CoA desaturase. Methods of using these compounds for modulation of stearoyl-CoA desaturase expression and for treatment of diseases associated with expression of stearoyl-CoA desaturase are provided.
Public/Granted literature
- US20080153766A1 Antisense modulation of stearoyl-CoA desaturase expression Public/Granted day:2008-06-26
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