Invention Grant
- Patent Title: Bivalent Smac mimetics and the uses thereof
- Patent Title (中): 二价Smac模拟物及其用途
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Application No.: US11800220Application Date: 2007-05-04
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Publication No.: US07960372B2Publication Date: 2011-06-14
- Inventor: Shaomeng Wang , Haiying Sun , Dongguang Qin , Zaneta Nikolovska-Coleska , Jianfeng Lu , Su Qiu , Yuefeng Peng , Qian Cai
- Applicant: Shaomeng Wang , Haiying Sun , Dongguang Qin , Zaneta Nikolovska-Coleska , Jianfeng Lu , Su Qiu , Yuefeng Peng , Qian Cai
- Applicant Address: US MI Ann Arbor
- Assignee: The Regents of the University of Michigan
- Current Assignee: The Regents of the University of Michigan
- Current Assignee Address: US MI Ann Arbor
- Agency: Casimir Jones SC
- Main IPC: A61K31/545
- IPC: A61K31/545 ; C07D225/00 ; C07D403/00
Abstract:
The invention relates to bivalent mimetics of Smac which function as inhibitors of Inhibitor of Apoptosis Proteins. The invention also relates to the use of these mimetics for inducing apoptotic cell death and for sensitizing cells to inducers of apoptosis.
Public/Granted literature
- US20080089896A1 Bivalent SMAC mimetics and the uses thereof Public/Granted day:2008-04-17
Information query
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