Invention Grant
US07960386B2 Pyridin-2-one compounds and their use as modulators of the dopamine D3 receptor
有权
吡啶-2-酮化合物及其作为多巴胺D3受体调节剂的用途
- Patent Title: Pyridin-2-one compounds and their use as modulators of the dopamine D3 receptor
- Patent Title (中): 吡啶-2-酮化合物及其作为多巴胺D3受体调节剂的用途
-
Application No.: US11628633Application Date: 2005-06-03
-
Publication No.: US07960386B2Publication Date: 2011-06-14
- Inventor: Herve Geneste , Wilfried Braje , Andreas Haupt
- Applicant: Herve Geneste , Wilfried Braje , Andreas Haupt
- Applicant Address: DE Wiesbaden
- Assignee: Abbott GmbH & Co. KG
- Current Assignee: Abbott GmbH & Co. KG
- Current Assignee Address: DE Wiesbaden
- Agency: Polsinelli Shughart PC
- Agent Lisa V. Mueller
- Priority: DE102004027359 20040604
- International Application: PCT/EP2005/006001 WO 20050603
- International Announcement: WO2005/118571 WO 20051215
- Main IPC: C07D401/12
- IPC: C07D401/12 ; A61K31/506

Abstract:
The invention relates to pyridin-2-one compounds of general formula (I) in which A represents a 4- to 6-membered hydrocarbon chain that can have 1 or 2 methyl groups as substituents, wherein 1 or 2 carbon atoms can be replaced by oxygen, a carbonyl group or sulfur, and the hydrocarbon chain can have a double bond or a triple bond; R1, R2, R3 and R4 have the meanings as cited in the claims and in the description. The invention also relates to the tautomers of compounds I and the physiologically acceptable salts of the compounds I and their tautomers.The invention also relates to the use of these compounds for treating diseases that respond to the influence of dopamine D3 receptor antagonists or agonists.
Public/Granted literature
- US20080261992A1 Pyridin-2-One Compounds and Their Use as Modulators of the Dopamine D3 Receptor Public/Granted day:2008-10-23
Information query