Invention Grant
- Patent Title: Regulation of TNF-alpha
- Patent Title (中): 调节TNF-α
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Application No.: US10419327Application Date: 2003-04-17
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Publication No.: US07960398B2Publication Date: 2011-06-14
- Inventor: Karen Miller , Anita Diu-Hercend , Thierry Hercend , Paul Lang , Peter Weber , Julian Golec , Michael Mortimore
- Applicant: Karen Miller , Anita Diu-Hercend , Thierry Hercend , Paul Lang , Peter Weber , Julian Golec , Michael Mortimore
- Applicant Address: US MA Cambridge
- Assignee: Vertex Pharmaceuticals Incorporated
- Current Assignee: Vertex Pharmaceuticals Incorporated
- Current Assignee Address: US MA Cambridge
- Agency: Ropes & Gray LLP
- Agent James F. Haley, Jr.; Yang Xu
- Main IPC: A61K31/517
- IPC: A61K31/517
Abstract:
The present invention relates to methods for identifying compounds useful for regulating TNF-alpha levels and/or activity. The invention also relates to methods for decreasing TNF-alpha levels and/or activity. Compounds and compositions according to this invention are useful for treating TNF-mediated diseases. The invention also relates to kits comprising the compounds and compositions herein and a tool for measuring TNF-alpha activity and/or levels.
Public/Granted literature
- US20040048797A1 Regulation of TNF-alpha Public/Granted day:2004-03-11
Information query
IPC分类:
