Invention Grant
- Patent Title: Benzazole potentiators of metabotropic glutamate receptors
- Patent Title (中): 代谢型谷氨酸受体的苯唑增强剂
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Application No.: US11884391Application Date: 2006-02-17
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Publication No.: US07960417B2Publication Date: 2011-06-14
- Inventor: Steven P. Govek , Jean-Michel Vernier , Theodore Kamenecka , John H. Hutchinson , Richard Pracitto
- Applicant: Steven P. Govek , Jean-Michel Vernier , Theodore Kamenecka , John H. Hutchinson , Richard Pracitto
- Applicant Address: US NJ Rahway
- Assignee: Merck Sharp & Dohme Corp.
- Current Assignee: Merck Sharp & Dohme Corp.
- Current Assignee Address: US NJ Rahway
- Agent Gerard Devlin; Raynard Yuro
- International Application: PCT/US2006/005711 WO 20060217
- International Announcement: WO2006/091496 WO 20060831
- Main IPC: A61K31/41
- IPC: A61K31/41 ; A61K31/4192 ; C07D403/12 ; C07D249/20 ; C07D249/18
Abstract:
The present invention is directed to benzazole compounds which are potentiators of metabotropic glutamate receptors, including the mGluR2 receptor, and which are useful in the treatment or prevention of neurological and psychiatric disorders associated with glutamate dysfunction and diseases in which metabotropic glutamate receptors are involved. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which metabotropic glutamate receptors are involved.
Public/Granted literature
- US20080176904A1 Benzazole Potentiators of Metabotropic Glutatmate Receptors Public/Granted day:2008-07-24
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