Invention Grant
US07960584B2 Compounds, isomer thereof, or pharmaceutically acceptable salts thereof as vanilloid receptor antagonist; and pharmaceutical compositions containing the same
有权
化合物，其异构体或其药学上可接受的盐作为香草素受体拮抗剂; 和含有它们的药物组合物
- Patent Title: Compounds, isomer thereof, or pharmaceutically acceptable salts thereof as vanilloid receptor antagonist; and pharmaceutical compositions containing the same
- Patent Title (中): 化合物，其异构体或其药学上可接受的盐作为香草素受体拮抗剂; 和含有它们的药物组合物
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Application No.: US11909144Application Date: 2006-03-17
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Publication No.: US07960584B2Publication Date: 2011-06-14
- Inventor: Young-Ger Suh , Hee-Doo Kim , Hyeung-Geun Park , Uh Taek Oh , Yong-Sil Lee , Seol Rin Park , Chong Hyon Ryu , Young-Ho Park , Song Seok Shin , Sun-Young Kim , Jin Kwan Kim , Yeon Su Jeong , Ki-Wha Lee , Jin Kyu Choi , Kyung Min Lim , Hyun Ju Koh , Joo Hyun Moh , Sung-II Kim , Joon Ho Bae
- Applicant: Young-Ger Suh , Hee-Doo Kim , Hyeung-Geun Park , Uh Taek Oh , Yong-Sil Lee , Seol Rin Park , Chong Hyon Ryu , Young-Ho Park , Song Seok Shin , Sun-Young Kim , Jin Kwan Kim , Yeon Su Jeong , Ki-Wha Lee , Jin Kyu Choi , Kyung Min Lim , Hyun Ju Koh , Joo Hyun Moh , Sung-II Kim , Joon Ho Bae
- Applicant Address: KR Seoul
- Assignee: Amorepacific Corporation
- Current Assignee: Amorepacific Corporation
- Current Assignee Address: KR Seoul
- Agency: Rothwell, Figg, Ernst & Manbeck, P.C.
- Priority: KR10-2005-0022986 20050319
- International Application: PCT/KR2006/000988 WO 20060317
- International Announcement: WO2006/101321 WO 20060928
- Main IPC: C07C311/02
- IPC: C07C311/02
Abstract:
This present invention relates to novel compounds, isomer thereof or pharmaceutically acceptable salts thereof as vanilloid receptor (Vanilloid Receptor 1; VR1; TRPV1) antagonist; and a pharmaceutical composition containing the same. The present invention provides a pharmaceutical composition for preventing or treating a disease such as pain, migraine, arthralgia, neuralgia, neuropathies, nerve injury, skin disorder, urinary bladder hypersensitiveness, irritable bowel syndrome, fecal urgency, a respiratory disorder, irritation of skin, eye or mucous membrane, stomach-duodenal ulcer, inflammatory diseases, ear disease, and heart disease.
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