Invention Grant
US07960585B2 Process for preparing secondary amides by carbonylation of a corresponding tertiary amine 有权
通过羰基化相应叔胺制备仲酰胺的方法

Process for preparing secondary amides by carbonylation of a corresponding tertiary amine
Abstract:
The present invention relates to a process for preparing secondary amides with good selectivity by carbonylating a corresponding tertiary amine with carbon monoxide in a reaction mixture in the presence of a metal catalyst and in the presence of a halogen containing promoter. The metal catalyst comprises palladium. A same or even a much better catalytic activity can be obtained with palladium than with the much more expensive rhodium, especially when the palladium is used in a low concentration. Moreover, also a good selectivity can be achieved.
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