An apparatus for cleaning a flat panel display and a roll brush used therein are provided. The apparatus includes an internal wall, hollow cylindrical joint parts, each of which is joined with the internal wall and having an opening therein, and roll brushes, each of which includes a rotation shaft passing through the opening of the hollow cylindrical joint part, a hollow cylindrical liquid blocking member integrated with the rotation shaft to have an inner diameter larger than an outer diameter of the joint part, and a brush.