Invention Grant
- Patent Title: Methods and compositions for treatment of myotonia
- Patent Title (中): 用于治疗肌强直的方法和组合物
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Application No.: US10591883Application Date: 2005-03-10
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Publication No.: US07964570B2Publication Date: 2011-06-21
- Inventor: Maurice S. Swanson , Rahul N. Kanadia , Charles A. Thornton
- Applicant: Maurice S. Swanson , Rahul N. Kanadia , Charles A. Thornton
- Applicant Address: US FL Gainesville
- Assignee: University of Florida Research Foundation, Inc.
- Current Assignee: University of Florida Research Foundation, Inc.
- Current Assignee Address: US FL Gainesville
- Agency: Edwards Angell Palmer & Dodge LLP Melissa Hunter-Ensor, Esq.
- Agent Peter F. Corless
- International Application: PCT/US2005/007631 WO 20050310
- International Announcement: WO2005/086825 WO 20050922
- Main IPC: A61K48/00
- IPC: A61K48/00 ; C12N5/00 ; C12N5/02 ; C07H21/02
Abstract:
The present invention provides methods and compositions for the treatment of diseases associated with aberrant microsatellite expansions. Methods of the present invention comprise the use of recombinant adeno-associated virus vectors containing a transgene encoding at least one muscleblind protein. The present invention also provides an animal model for a disease associated with aberrant microsatellite expansion.
Public/Granted literature
- US20080213182A1 Methods and Compositions for Treatment of Diseases Associated with Aberrant Microsatellite Expansion Public/Granted day:2008-09-04
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