Invention Grant
US07964598B2 ApoE4 domain interaction inhibitors and methods of use thereof
有权
ApoE4结构域相互作用抑制剂及其使用方法
- Patent Title: ApoE4 domain interaction inhibitors and methods of use thereof
- Patent Title (中): ApoE4结构域相互作用抑制剂及其使用方法
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Application No.: US11244268Application Date: 2005-10-04
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Publication No.: US07964598B2Publication Date: 2011-06-21
- Inventor: Robert W. Mahley , Karl H. Weisgraber , Yadong Huang
- Applicant: Robert W. Mahley , Karl H. Weisgraber , Yadong Huang
- Applicant Address: US CA San Francisco
- Assignee: The J. David Gladstone Institutes
- Current Assignee: The J. David Gladstone Institutes
- Current Assignee Address: US CA San Francisco
- Agency: Bozicevic, Field & Francis LLP
- Agent Paula A. Borden
- Main IPC: A61K31/535
- IPC: A61K31/535 ; A61K31/42 ; A61K31/38 ; A01N43/76 ; A01N43/12 ; C07D498/00 ; C07D487/00
Abstract:
The present invention provides compounds that inhibit apoE4 domain interaction; and compositions, including pharmaceutical compositions, comprising the compounds. The present invention provides methods of treating apoE4-related disorders. The methods generally involve administering to an individual in need thereof a therapeutically effective amount of an apoE4 domain interaction inhibitor.
Public/Granted literature
- US20060073104A1 ApoE4 domain interaction inhibitors and methods of use thereof Public/Granted day:2006-04-06
Information query
