Invention Grant
- Patent Title: Treatment of neurodegenerative conditions
- Patent Title (中): 治疗神经退行性疾病
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Application No.: US10567778Application Date: 2004-08-13
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Publication No.: US07964641B2Publication Date: 2011-06-21
- Inventor: Laurence S. Harbige , Michael J. Leach , Mohammed Sharief , Paul Barraclough
- Applicant: Laurence S. Harbige , Michael J. Leach , Mohammed Sharief , Paul Barraclough
- Applicant Address: GB London
- Assignee: BTG International Limited
- Current Assignee: BTG International Limited
- Current Assignee Address: GB London
- Agency: Nixon & Vanderhye
- Priority: GB0319358.8 20030818; GB0410846.0 20040514
- International Application: PCT/GB2004/003524 WO 20040813
- International Announcement: WO2005/018632 WO 20050303
- Main IPC: A61K31/201
- IPC: A61K31/201 ; C07C57/03 ; A61P25/00

Abstract:
A method is provided for treating a patient in need of therapy for a neurodegenerative disease comprising administering to that patient a therapeutically effective dose of a lipid glyceride comprising a glycerol moiety and a fatty acid moiety, the fatty acid moiety being selected from the group consisting of γ-linolenic acid, dihomo-γ-linolenic acid and arachidonic acid characterized in that the selected fatty acid moiety is attached to the glycerol moiety at its sn-2 position. Preferably the method is that wherein the lipid is administered for a duration and at a dose sufficient to maintain or elevate TGF-β1 levels in the patient to therapeutic levels.
Public/Granted literature
- US20080194684A1 Treatment of Neurodegenerative Conditions Public/Granted day:2008-08-14
Information query
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