Invention Grant
- Patent Title: Gene expression suppression agents
- Patent Title (中): 基因表达抑制剂
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Application No.: US10552909Application Date: 2003-05-12
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Publication No.: US07964714B2Publication Date: 2011-06-21
- Inventor: Yingxian Xiao , Xin-Hua Feng
- Applicant: Yingxian Xiao , Xin-Hua Feng
- Applicant Address: US MD Potomac
- Assignee: Potomac Pharmaceuticals Inc.
- Current Assignee: Potomac Pharmaceuticals Inc.
- Current Assignee Address: US MD Potomac
- Agency: Shook, Hardy & Bacon LLP
- International Application: PCT/US03/14631 WO 20030512
- International Announcement: WO2004/106488 WO 20041209
- Main IPC: C12Q1/68
- IPC: C12Q1/68 ; C12P19/34 ; C12N15/00 ; C07H21/02 ; C07H21/04
Abstract:
A method is provided for making gene suppression agents to be used in eukaryotic cells by using a recombinant DNA construct containing at least one transcriptional unit compromising a transcriptional promoter, a template sequence for making a RNA molecule, and a transcriptional terminator. Mechanisms of the RNA mediated gene suppression include, but are not limited to, RNA interferences (RNAi). The use of the agents as tools for biomedical research as well as medicinal products is also disclosed.
Public/Granted literature
- US20070105795A1 Gene expression suppression agents Public/Granted day:2007-05-10
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